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EFFECTIVENESS OF PILATES AND CAMELLIA SINENSIS SUPPLEMENTATION ON CARDIOMETABOLIC RISK FACTORS AND REDOX MARKERS IN POSTMENOPAUSAL WOMEN: A PLACEBO-CONTROLLED, RANDOMIZED TRIAL

S. Junges, R. Dias Molina, C. Bittencourt Jacondino, M. Lopes Da Poian, E. Tatsch, R. Noal Moresco, M.G. Valle Gottlieb

J Aging Res Clin Practice 2017;6:80-87

Objective: To verify the effectiveness of Pilates and Camellia sinensis extract (CSE) supplementation on cardiometabolic risk factors and redox markers in postmenopausal women. Design: A placebo-controlled, randomized trial. Setting: community-dwelling postmenopausal women without disability. Participants: fifty postmenopausal women volunteers with cardiometabolic risk factors (high waist circumference, triglycerides, HDL-c, glucose and blood pressure). The volunteers participants were randomized in four groups: Pilates+CSE (14); Pilates+Placebo (11); CSE (11); and Placebo (14). Intervention: the CSE and Pilates+CSE intervention groups consumed one 500mg CSE capsule with excipient per day for 24 weeks. The Placebo group consumed one capsule with a placebo excipient per day for 24 weeks. Pilates training was performed twice weekly for 60 minutes each time, over 24 weeks. Measurements: cardiometabolic risk factors (glucose, waist circumference (WC), systolic blood pressure (SBP), diastolic blood pressure (DBP), triglycerides, high-density lipoproteins-HDL-c) and oxidative metabolism markers (advanced oxidation protein products (AOPP), ferric-reducing ability of plasma (FRAP), nitrosative stress marker (NOx), ischemia modified albumin (IMA). Results: When baseline variables were adjusted, the WC of the Pilates + CSE was significantly lower than that of the CSE and Placebo groups after the intervention (p<0,001).The triglycerides levels of the Pilates + CSE and Pilates + Placebo groups were significantly lower than those of the Placebo group (p= 0,010) . The glucose levels of the Pilates + CSE group were significantly lower than those of the Placebo group (p= 0,041). Whitin-group pre and post intervention comparison showed that Pilates+CSE group presented the best effect in some cardiometabolic risk factors, with significant reductions in tree cardiometabolic risk factor: waist circumference, triglycerides, glucose and FRAP (P=0.003, P<0.001, P=0.021 and P=0.041, respectively). The Pilates+Placebo group was found to be effective in reducing triglycerides (P=0.002), while the CSE group presented increased post-intervention NOx levels (p= 0.009). Conclusion: Our results suggest that Pilates and Camellia sinensis extract intervention may help to reduce some cardiometabolic risk factors in postmenopausal women.

CITATION:
S. Junges ; R. Dias Molina ; C. Bittencourt Jacondino ; M. Lopes Da Poian ; E. Tatsch ; R. Noal Moresco ; M.G. Valle Gottlieb (2017): EFFECTIVENESS OF PILATES AND CAMELLIA SINENSIS SUPPLEMENTATION ON CARDIOMETABOLIC RISK FACTORS AND REDOX MARKERS IN POSTMENOPAUSAL WOMEN: A PLACEBO-CONTROLLED, RANDOMIZED TRIAL. The Journal of Aging Research and Clinical Practice (JARCP). http://dx.doi.org/10.14283/jarcp.2017.7

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