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REGULAR CAFFEINE CONSUMPTION & SUBJECTIVE SLEEP QUALITY: A SYSTEMATIC REVIEW

Duc Minh Phan (Tommy), My Yen Lam, Minh Nguyet Trang

J Aging Res & Lifestyle 2025;14

Caffeine, the world's most consumed stimulant, is commonly used to combat fatigue, This review examined the unclear relationship between long-term caffeine consumption and subjective sleep quality, defined as satisfaction with sleep based on personal perception. Screening 6,908 studies, 10 were included. Results showed limited statistically significant associations, hindered by variability in study quality, data, and assessment methods. Influencing factors such as individual differences and study heterogeneity were identified. The review highlights the need for standardized tools and methodologies, urging future research to explore genetic, cultural, and timing factors to better understand caffeine's impact on sleep quality.

CITATION:
Duc Minh Phan (Tommy) ; My Yen Lam ; Minh Nguyet Trang (2025): Regular caffeine consumption & subjective sleep quality: A systematic review. The Journal of Aging and Lifestyle (JARLife). https://doi.org/10.1016/j.jarlif.2025.100005

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ADHERENCE AND AEROBIC EXERCISE INTENSITY IN LIVE ONLINE EXERCISE SESSIONS FOR OLDER ADULTS WITH MILD COGNITIVE IMPAIRMENT: INSIGHTS FROM THE JAPAN-MULTIMODAL INTERVENTION TRIAL FOR THE PREVENTION OF DEMENTIA

Taiki Sugimoto, Kazuaki Uchida, Yoko Yokoyama, Ayaka Onoyama, Kosuke Fujita, Yujiro Kuroda, Keigo Hinakura, Susumu Ogawa, Hiroyuki Suzuki, Yoshinori Fujiwara, Paul K Crane, Hidenori Arai, Takashi Sakurai, J-MINT study group

J Aging Res & Lifestyle 2025;14

BACKGROUND: Intervention adherence is crucial to ensure cognitive benefits in trials designed to prevent cognitive decline. During the coronavirus disease 2019 (COVID-19) pandemic, the Japan-Multimodal Intervention Trial for the Prevention of Dementia offered live online exercise sessions to older adults with mild cognitive impairment (MCI). OBJECTIVES: To assess adherence and aerobic exercise intensity through live online exercise sessions in older adults with MCI. DESIGN: Posthoc analysis of the 18-month, multi-center, randomized controlled trial. SETTING: The study was conducted across five institutions in Japan. PARTICIPANTS: Older adults aged 65–85 years who were assigned to the intervention group and completed the intervention. Participants were stratified by region (Aichi and Tokyo), where the state of emergency duration due to COVID-19 varied. INTERVENTIONS: The intervention group participated in multidomain interventions, including 90-minute group-based physical exercise sessions held weekly for 78 sessions. During the state of emergency, live online sessions were conducted via video conferencing. MEASUREMENTS: Attendance rates and aerobic exercise intensity (based on heart rates) during online and onsite sessions were compared using the Wilcoxon signed-rank test. RESULTS: A total of 207 participants were analyzed. Over 18 months, 78 exercise sessions were conducted, including live online sessions. In the Aichi region, 2 online sessions were held, while in the Tokyo region, 24 online sessions were conducted. In the Tokyo region, adherence was higher in online sessions compared to onsite sessions (92 % vs. 86 %, p = 0.046), while exercise intensity showed no significant difference (49 % vs. 52 %, p = 0.279). No adverse events were reported. CONCLUSIONS: Live online exercise sessions were safe, feasible, and demonstrated adherence and intensity comparable to onsite sessions.

CITATION:
Taiki Sugimoto ; Kazuaki Uchida ; Yoko Yokoyama ; Ayaka Onoyama ; Kosuke Fujita ; Yujiro Kuroda ; Keigo Hinakura ; Susumu Ogawa ; Hiroyuki Suzuki ; Yoshinori Fujiwara ; Paul K Crane ; Hidenori Arai ; Takashi Sakurai ; J-MINT study group (2025): Adherence and aerobic exercise intensity in live online exercise sessions for older adults with mild cognitive impairment: Insights from the Japan-Multimodal Intervention Trial for the Prevention of Dementia. The Journal of Aging and Lifestyle (JARLife). https://doi.org/10.1016/j.jarlif.2025.100003

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CONTRIBUTION OF PHYSICAL ACTIVITY TO INTRINSIC CAPACITY DIFFERS IN USA, UK, EUROPE AND CHINA

Z Huang, ETC Lai, J Woo

J Aging Res & Lifestyle 2025;14

BACKGROUND: Within-country studies show that physical activity is associated with better intrinsic capacity. OBJECTIVES: To examine whether the contribution of physical activity to intrinsic capacity varies between countries due to varying social determinants, and whether physical activity associates differently with only certain domains of intrinsic capacity. DESIGN: Prospective cohort studies. SETTING: Populations of the USA, UK, Europe, and China. PARTICIPANTS: Nationally representative samples of middle-aged and older adults who were interviewed every two or three years. MEASUREMENTS: Intrinsic capacity was assessed according to the following domains: locomotor, vitality, cognition, vision and hearing, and psychological health. Physical activity was defined as taking part in vigorous or moderate physical activity was more than weekly. RESULTS: Physical activity was associated with better intrinsic capacity in both genders in USA, UK, and Europe, but not in China. In these developed countries, physical activity was associated with all domains of intrinsic capacity, except for cognition in men in the UK. The largest effect sizes were observed in the domains of locomotion, psychological health, and vitality. In China, physical activity was significantly and positively associated with two domains of intrinsic capacity (vitality and locomotion) for men and women only in rural areas. CONCLUSIONS: Physical activity may contribute differently to intrinsic capacity, perhaps as a result of cultural and economic differences between countries.

CITATION:
Z Huang ; ETC Lai ; J Woo (2025): Contribution of physical activity to intrinsic capacity differs in USA, UK, Europe and China. The Journal of Aging and Lifestyle (JARLife). https://doi.org/10.1016/j.jarlif.2025.100007

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INCREMENTAL PREDICTIVE VALUE OF INTRINSIC CAPACITY AND ENVIRONMENTAL CHARACTERISTICS IN THE RISK PREDICTION OF INCIDENT DISABILITY

Ruby Yu, Grace Leung, Derek Lai, Lok-yan Tam, Clara Cheng, Sara Kong, Cecilia Tong, Jean Woo

J Aging Res & Lifestyle 2025;14

OBJECTIVE: To examine the incremental value of intrinsic capacity (IC) and environmental characteristics in the risk prediction of disability. METHODS: Secondary analysis was performed on a longitudinal sample of individuals aged 50 years or above. The selected subsample was ambulant and cognitively intact, and did not have any disabilities in instrumental activities of daily living (IADL) at baseline. A set of 18 indicators were first used to assess conditions associated with declines in IC and environmental characteristics. Participants were then followed up for approximately one year, and the IADL status (i.e., disabled or not) was treated as the outcome variable in the logistic regression models. The incremental predictive value of IC was examined by comparing the baseline model that only included traditional risk factors (e.g., health conditions and lifestyle factors), against the full model that also included the aforementioned 18 indicators. The comparison was performed using the change in area under the receiver operating characteristic curve (ROCAUC) and the continuous net reclassification index (NRI). RESULTS: Among 10,993 participants (mean age = 73.3, 82.1 % women), 680 (6.2 %) developed disability during the concerned period. The full model significantly outperformed the baseline model, with the ROCAUC improving from 0.707 to 0.729 (change = 0.021; 95 % CI: 0.013–0.030). The continuous NRI was 0.361 (95 % bootstrap CI: 0.280–0.450). CONCLUSIONS: Measurements of IC and environmental characteristics have a significant incremental value in predicting disability. In practice, the full model can be implemented as a calculator for identifying older populations at risk of disability in the community settings.

CITATION:
Ruby Yu ; Grace Leung ; Derek Lai ; Lok-yan Tam ; Clara Cheng ; Sara Kong ; Cecilia Tong ; Jean Woo (2025): Incremental predictive value of intrinsic capacity and environmental characteristics in the risk prediction of incident disability. The Journal of Aging and Lifestyle (JARLife). https://doi.org/10.1016/j.jarlif.2025.100004

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PRE-SURGICAL MEMORY IMPAIRMENT IS ASSOCIATED WITH RISK OF POSTOPERATIVE COGNITIVE DYSFUNCTION IN A LARGE GERIATRIC COHORT

Kiri T. Granger, Claudia Spies, Sheryl Caswell, Daniel Hadzidiakos, Saya Speidel, Arjen JC Slooter, Ilse Kant, Sophie K Piper, Simone JT van Montfort, Jennifer H. Barnett, Paula M. Moran, Friedrich Borchers

J Aging Res & Lifestyle 2025;14

Some patients undergoing surgical procedures display long-term post-surgery cognitive impairment (post-operative cognitive dysfunction; POCD), which may precipitate progression to dementia. We investigated whether preoperative cognitive impairment defined using specific cognitive tests (Paired-Associates Learning and Spatial-Span from the Cambridge Neuropsychological Test Automated Battery, (CANTAB) was associated with increased risk of POCD. N = 590 patients >65years and a matched control group n=114 comprised the final sample. Patients were classified as impaired if a composite memory-score derived from two tests from the CANTAB test battery (spatial working memory and paired-associate learning) scored 1 SD below norms derived from a normative database. Risk of developing POCD 3 months post-surgery was higher [odds ratio 2.048 (95% CI 1.027 – 4.087)] for those with pre-surgical cognitive impairment compared to those with no impairment. This suggests that impairment on hippocampus-based tasks spatial-span memory and paired-associates learning is associated with increased risk for POCD in older surgical patients.

CITATION:
Kiri T. Granger ; Claudia Spies ; Sheryl Caswell ; Daniel Hadzidiakos ; Saya Speidel ; Arjen JC Slooter ; Ilse Kant ; Sophie K Piper ; Simone JT van Montfort ; Jennifer H. Barnett ; Paula M. Moran ; Friedrich Borchers (2025): Pre-surgical memory impairment is associated with risk of postoperative cognitive dysfunction in a large geriatric cohort. The Journal of Aging and Lifestyle (JARLife). https://doi.org/10.1016/j.jarlif.2025.100002

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